Affective response and cognition in HIV

Resource allocation theory, Polich (2007) suggests cortical measures may attenuate when processing demands increase. Thirteen HIV-negative women (M = 36.5) and 15 HIV-positive women (M = 36.1) infected were instructed to view neutral and negative IAPS images and then to detect rare tones in a subsequent auditory oddball task. A 2 x 2 ANOVA for the auditory P3 did not indicate a main effect for picture valence however an interaction was found between picture valence and serostatus at location Fz, F(1,24) = 18.99, p<.001. During the visual ERP sequence an interaction between valence and serostatus was found at the Pz location, F(1,24) = 18.99, p<.001, meaning the late positive potential (LPP) was not modulated between viewing neutral and negative images in HIV-positive women. These findings suggest that the manifestation of HIV in women may alter the neural processing of emotions, though not to the detriment of a subsequent cognitive task.