Note
Thesis (M.S.)--Florida Atlantic University, 1974.
Member of
Contributors
Publisher
Florida Atlantic University
Date Issued
1974
Description
Liver, kidney and spleen cells from healthy horses
and horses with equine infectious anemia were cultured
in vitro. Primary culture of organs from healthy horses
yielded typical elongate fibroblast cells. Primary culture
of organs from diseased horses yielded a variety of cell
types; pleomorphic giant cells being most common. The giant
cells did not divide, but either underwent degeneration and
death or became transformed into squamous-like cells lacking
contact inhibition resulting in the production of foci.
Inoculation of normal equine fibroblasts with either serum,
plasma, or liver, kidney or spleen extracts from diseased
horses resulted in a proliferation of the fibroblasts. Normal liver or kidney fibroblasts cocultivated with equine
leucocytes and inoculated with serum or plasma from a diseased
horse became transformed. This research supports the
proposal that equine infectious anemia virus is an oncornavirus.
and horses with equine infectious anemia were cultured
in vitro. Primary culture of organs from healthy horses
yielded typical elongate fibroblast cells. Primary culture
of organs from diseased horses yielded a variety of cell
types; pleomorphic giant cells being most common. The giant
cells did not divide, but either underwent degeneration and
death or became transformed into squamous-like cells lacking
contact inhibition resulting in the production of foci.
Inoculation of normal equine fibroblasts with either serum,
plasma, or liver, kidney or spleen extracts from diseased
horses resulted in a proliferation of the fibroblasts. Normal liver or kidney fibroblasts cocultivated with equine
leucocytes and inoculated with serum or plasma from a diseased
horse became transformed. This research supports the
proposal that equine infectious anemia virus is an oncornavirus.
Language
Type
Form
Extent
76 p.
Subject (Topical)
Identifier
13651
Additional Information
Thesis (M.S.)--Florida Atlantic University, 1974.
Date Backup
1974
Date Text
1974
Date Issued (EDTF)
1974
Extension
FAU
FAU
admin_unit="FAU01", ingest_id="ing1508", creator="staff:fcllz", creation_date="2007-07-19 01:24:48", modified_by="staff:fcllz", modification_date="2011-01-06 13:09:01"
IID
FADT13651
Issuance
monographic
Organizations
Attributed name: Florida Atlantic University
Person Preferred Name
MANKAMYER, MARY PAT
Graduate College
Physical Description
76 p.
application/pdf
Title Plain
CELL CULTURE RESPONSES TO EQUINE INFECTIOUS ANEMIA VIRUS
Use and Reproduction
Copyright © is held by the author with permission granted to Florida Atlantic University to digitize, archive and distribute this item for non-profit research and educational purposes. Any reuse of this item in excess of fair use or other copyright exemptions requires permission of the copyright holder.
http://rightsstatements.org/vocab/InC/1.0/
Origin Information
1974
monographic
Boca Raton, Fla.
Florida Atlantic University
Physical Location
Florida Atlantic University Libraries
Place
Boca Raton, Fla.
Sub Location
Digital Library
Title
CELL CULTURE RESPONSES TO EQUINE INFECTIOUS ANEMIA VIRUS
Other Title Info
CELL CULTURE RESPONSES TO EQUINE INFECTIOUS ANEMIA VIRUS