Note
by Andrew Smith.
Member of
Contributors
Publisher
Florida Atlantic University
Date Issued
2010
Description
The Major Histocompatibility Complex class II B (MHC II B) gene encodes a protein that is part of the adaptive immune system and critical for the non-self recognition ability of immune cells. This gene has been characterized in the Bald Eagle, ten unique alleles were found in two subpopulations at the geographic extremes of the range margins. Geographic genetic variation is suggested by the presence of population specific alleles. The results showed considerable divergence of groups of Bald Eagle alleles when compared to alleles from other birds of prey. Particular codons within the exon II show signs of balancing selection driving the evolution of the MHC II B. Transcription data showed statistically significant differential expression of alleles. This can be interpreted as meaning a particular locus is being preferentially expressed in blood. The analysis of the polymorphism of this adaptive marker may aid managers of wildlife during this age of global climate change and the biodiversity crisis.
Language
Type
Form
Extent
viii, 48 p. : ill.
Subject (Topical)
Identifier
705370102
OCLC Number
705370102
Additional Information
by Andrew Smith.
Thesis (M.S.)--Florida Atlantic University, 2010.
Includes bibliography.
Electronic reproduction. Boca Raton, Fla., 2010. Mode of access: World Wide Web.
Date Backup
2010
Date Text
2010
Date Issued (EDTF)
2010
Extension
FAU
FAU
admin_unit="FAU01", ingest_id="ing8977", creator="creator:NBURWICK", creation_date="2011-03-07 16:07:43", modified_by="super:SPATEL", modification_date="2012-01-23 12:09:54"
IID
FADT2979375
Organizations
Attributed name: Charles E. Schmidt College of Science
Attributed name: Department of Biological Sciences
Person Preferred Name
Smith, Andrew.
Graduate College
Physical Description
electronic
viii, 48 p. : ill.
Title Plain
Characterization of the MHC II B of the bald eagle
Use and Reproduction
http://rightsstatements.org/vocab/InC/1.0/
Origin Information
Boca Raton, Fla.
Florida Atlantic University
2010
Place
Boca Raton, Fla.
Title
Characterization of the MHC II B of the bald eagle
Other Title Info
Characterization of the MHC II B of the bald eagle