The objective of research in progress in our laboratory is to establish cell lines of bioactive marine invertebrates that can be used as models to study in vitro production of bioactive metabolites and the factors which control expression of production. We hypothesize that understanding the molecular mechanisms involved in growth regulation and bioactive metabolite production in these organisms will lead to the development of genetically engineered cell-lines capable of overexpression of bioactive natural products. Perhaps more important, however, is the development of cell lines of these 'simple' metazoans to study basic cell physiology and molecular biology that may be applied to understanding more complex metazoan systems, including humans.
Member of
Contributors
Publisher
Springer-Verlag
Date Issued
2000
Note
Language
Type
Genre
Extent
15 p.
Subject (Topical)
Identifier
3172822
Additional Information
The objective of research in progress in our laboratory is to establish cell lines of bioactive marine invertebrates that can be used as models to study in vitro production of bioactive metabolites and the factors which control expression of production. We hypothesize that understanding the molecular mechanisms involved in growth regulation and bioactive metabolite production in these organisms will lead to the development of genetically engineered cell-lines capable of overexpression of bioactive natural products. Perhaps more important, however, is the development of cell lines of these 'simple' metazoans to study basic cell physiology and molecular biology that may be applied to understanding more complex metazoan systems, including humans.
This manuscript is an author version with the final publication available at http://www.springerlink.com and may be cited as: Pomponi, S. A., & Willoughby, R. (2000). Development of sponge cell cultures for biomedical application. In C. Mothersill & B. Austin (Eds.). Aquatic invertebrate cell culture. (pp. 323-336). Berlin: Springer-Verlag.
Florida Atlantic University. Harbor Branch Oceanographic Institute contribution #1343.
Date Backup
2000
Date Text
2000
Date Issued (EDTF)
2000
Extension
FAU
FAU
admin_unit="FAU01", ingest_id="ing10057", creator="creator:BCHANG", creation_date="2011-07-21 14:29:14", modified_by="super:FAUDIG", modification_date="2014-02-11 10:31:50"
IID
FADT3172822
Issuance
single unit
Person Preferred Name
Pomponi, Shirley A.
creator
spomponi@fau.edu
Physical Description
15 p.
Title Plain
Development of sponge cell cultures for biomedical application
Origin Information
Springer-Verlag
2000
single unit
Title
Development of sponge cell cultures for biomedical application
Other Title Info
Development of sponge cell cultures for biomedical application