Note
There is a tremendous level of worldwide interest in marine natural productswith therapeutic potential in industry, academia, and government resea rchlabs, largely because natural products generally continue to be viewed as o neof the few de novo sources of drug discovery, yielding unorthodox and oftenunexpected chemical st ructures that offer nove l points of de pa rture for molecularmodification leading to clinically ava il able drugs (de Souza et a l. 1982).