Note
Includes bibliography.
Member of
Contributors
Publisher
Florida Atlantic University
Date Issued
2018
EDTF Date Created
2018
Description
Since the release of the Cyberknife Multileaf Collimator (CK-MLC), it has been a constant
concern on the realistic dose differences computed with its early-available Finite Size
Pencil Beam algorithm (FSPB) from those computed by using industry well-accepted
algorithms such as the Monte Carlo (MC) dose algorithm. In this study dose disparities
between FSPB and MC dose calculation algorithms for selected CK-MLC treatment plans
were quantified. The dosimetry for planning target volume (PTV) and major organs at risks
(OAR) was compared by calculating normalized percentage deviations (Ndev) between the
two algorithms. It is found that the FSPB algorithm overestimates D95 of PTV when
compared with the MC algorithm by averaging 24.0% in detached lung cases, and 15.0%
in non-detached lung cases which is attributed to the absence of heterogeneity correction
in the FSPB algorithm. Average dose differences are 0.3% in intracranial and 0.9% in
pancreas cases. Ndev for the D95 of PTV range from 8.8% to 14.1% for the CK-MLC lung
treatment plans with small field (SF ≤ 2x2cm2). Ndev is ranged from 0.5-7.0% for OARs.
concern on the realistic dose differences computed with its early-available Finite Size
Pencil Beam algorithm (FSPB) from those computed by using industry well-accepted
algorithms such as the Monte Carlo (MC) dose algorithm. In this study dose disparities
between FSPB and MC dose calculation algorithms for selected CK-MLC treatment plans
were quantified. The dosimetry for planning target volume (PTV) and major organs at risks
(OAR) was compared by calculating normalized percentage deviations (Ndev) between the
two algorithms. It is found that the FSPB algorithm overestimates D95 of PTV when
compared with the MC algorithm by averaging 24.0% in detached lung cases, and 15.0%
in non-detached lung cases which is attributed to the absence of heterogeneity correction
in the FSPB algorithm. Average dose differences are 0.3% in intracranial and 0.9% in
pancreas cases. Ndev for the D95 of PTV range from 8.8% to 14.1% for the CK-MLC lung
treatment plans with small field (SF ≤ 2x2cm2). Ndev is ranged from 0.5-7.0% for OARs.
Language
Type
Form
Extent
85 p.
Subject (Topical)
Identifier
FA00013123
Additional Information
Includes bibliography.
Thesis (M.S.)--Florida Atlantic University, 2018.
FAU Electronic Theses and Dissertations Collection
Date Backup
2018
Date Created Backup
2018
Date Text
2018
Date Created (EDTF)
2018
Date Issued (EDTF)
2018
Extension
FAU
IID
FA00013123
Organizations
Attributed name: Florida Atlantic University
Attributed name: Charles E. Schmidt College of Science
Attributed name: Department of Physics
Person Preferred Name
Galpayage Dona, Kalpani Nisansala Udeni
author
Graduate College
Physical Description
application/pdf
85 p.
Title Plain
Dosimetry comparison between treatment plans computed with Finite size pencil beam algorithm and Monte Carlo algorithm using InCise™ Multileaf collimator equipped CyberKnife® System
Use and Reproduction
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http://rightsstatements.org/vocab/InC/1.0/
Origin Information
2018
2018
Florida Atlantic University
Boca Raton, Fla.
Physical Location
Florida Atlantic University Libraries
Place
Boca Raton, Fla.
Sub Location
Digital Library
Title
Dosimetry comparison between treatment plans computed with Finite size pencil beam algorithm and Monte Carlo algorithm using InCise™ Multileaf collimator equipped CyberKnife® System
Other Title Info
Dosimetry comparison between treatment plans computed with Finite size pencil beam algorithm and Monte Carlo algorithm using InCise™ Multileaf collimator equipped CyberKnife® System