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Glial Hsp70 Protects K+ Homeostasis in the Drosophila Brain during Repetitive Anoxic Depolarization
Type: Text
Year: 2011, 2011
Member of: FAU College Collections
Contributors: Armstrong, Gary A. B., Dawson-Scully, Ken, Krill, Jennifer L., Robertson, R. Meldrum, Roman, Gregg, Seroude, Laurent, Xiao, Chengfeng
Description: Neural tissue is particularly vulnerable to metabolic stress and loss of ion homeostasis. Repetitive stress generally leads to
more permanent dysfunction but the mechanisms underlying this progression are poorly understood. We investigated the
effects of energetic compromise in Drosophila by targeting the Na+/K+-ATPase. Acute ouabain treatment of intact flies
resulted in subsequent repetitive… more
Full Text: Glial Hsp70 Protects K+ Homeostasis in the Drosophila Brain during Repetitive Anoxic Depolarization Gary A. B. Armstrong1*, Chengfeng Xiao1, Jennifer L. Krill2, Laurent Seroude1, Ken Dawson-Scully2, R. Meldrum Robertson1 1 Department of Biology, Queen’s …