FAU College Collections
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Glial Hsp70 Protects K+ Homeostasis in the Drosophila Brain during Repetitive Anoxic Depolarization
Type: Text
Year: 2011, 2011
Member of: FAU College Collections
Contributors: Armstrong, Gary A. B., Dawson-Scully, Ken, Krill, Jennifer L., Robertson, R. Meldrum, Roman, Gregg, Seroude, Laurent, Xiao, Chengfeng
Description: Neural tissue is particularly vulnerable to metabolic stress and loss of ion homeostasis. Repetitive stress generally leads to
more permanent dysfunction but the mechanisms underlying this progression are poorly understood. We investigated the
effects of energetic compromise in Drosophila by targeting the Na+/K+-ATPase. Acute ouabain treatment of intact flies
resulted in subsequent repetitive… more
Full Text: Glial Hsp70 Protects K+ Homeostasis in the Drosophila Brain during Repetitive Anoxic Depolarization Gary A. B. Armstrong1*, Chengfeng Xiao1, Jennifer L. Krill2, Laurent Seroude1, Ken Dawson-Scully2, R. Meldrum Robertson1 1 Department of Biology, Queen’s …
cGMP-Dependent Protein Kinase Inhibition Extends the Upper Temperature Limit of Stimulus-Evoked Calcium Responses in Motoneuronal Boutons of Drosophila melanogaster Larvae
Type: Text
Year: 2016, 2016
Member of: FAU College Collections
Contributors: Dawson-Scully, Ken, Krill, Jennifer L., McCabe, Brian D.
Description: While the mammalian brain functions within a very narrow range of oxygen concentrations
and temperatures, the fruit fly, Drosophila melanogaster, has employed strategies to deal
with a much wider range of acute environmental stressors. The foraging (for) gene encodes
the cGMP-dependent protein kinase (PKG), has been shown to regulate thermotolerance
in many stress-adapted species, including… more
Full Text: RESEARCH ARTICLE cGMP-Dependent Protein Kinase Inhibition Extends the Upper Temperature Limit of Stimulus-Evoked Calcium Responses in Motoneuronal Boutons of Drosophila melanogaster Larvae Jennifer L. Krill, Ken Dawson-Scully* Department of Biological …