FAU College Collections
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New Tools for Targeted Disruption of Cholinergic Synaptic Transmission in Drosophila melanogaster
Type: Text
Year: 2013, 2013
Member of: FAU College Collections
Contributors: Godenschwege, Tanja A., Heghinian, Mari D., Mari, Frank, McCabe, Brian D., Mejia, Monica
Description: Nicotinic acetylcholine receptors (nAChRs) are pentameric ligand-gated ion channels. The a7 subtype of nAChRs is involved
in neurological pathologies such as Parkinson’s disease, Alzheimer’s disease, addiction, epilepsy and autism spectrum
disorders. The Drosophila melanogaster a7 (Da7) has the closest sequence homology to the vertebrate a7 subunit and it can
form homopentameric receptors just… more
Full Text: New Tools for Targeted Disruption of Cholinergic Synaptic Transmission in Drosophila melanogaster Monica Mejia1, Mari D. Heghinian2, Frank Marı́2, Tanja A. Godenschwege3* 1 Department of Biological Sciences, Florida Atlantic University, Boca Raton, …
cGMP-Dependent Protein Kinase Inhibition Extends the Upper Temperature Limit of Stimulus-Evoked Calcium Responses in Motoneuronal Boutons of Drosophila melanogaster Larvae
Type: Text
Year: 2016, 2016
Member of: FAU College Collections
Contributors: Dawson-Scully, Ken, Krill, Jennifer L., McCabe, Brian D.
Description: While the mammalian brain functions within a very narrow range of oxygen concentrations
and temperatures, the fruit fly, Drosophila melanogaster, has employed strategies to deal
with a much wider range of acute environmental stressors. The foraging (for) gene encodes
the cGMP-dependent protein kinase (PKG), has been shown to regulate thermotolerance
in many stress-adapted species, including… more
Full Text: RESEARCH ARTICLE cGMP-Dependent Protein Kinase Inhibition Extends the Upper Temperature Limit of Stimulus-Evoked Calcium Responses in Motoneuronal Boutons of Drosophila melanogaster Larvae Jennifer L. Krill, Ken Dawson-Scully* Department of Biological …