FAU College Collections
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egl‑4 modulates electroconvulsive seizure duration in C. elegans
Type: Text
Year: 2018, 2018
Member of: FAU College Collections
Contributors: Justin Minnerly, Kailiang Jia, Ken Dawson‑Scully, Monica G. Risley, Stephanie P. Kelly
Publisher: Springer Nature
Description: Increased neuronal excitability causes seizures with debilitating symptoms. Effective and noninvasive treatments are limited
for easing symptoms, partially due to the complexity of the disorder and lack of knowledge of specific molecular faults. An
unexplored, novel target for seizure therapeutics is the cGMP/protein kinase G (PKG) pathway, which targets downstream
K+
channels, a mechanism… more
Full Text: Invertebrate Neuroscience (2018) 18:8 https://doi.org/10.1007/s10158-018-0211-9 ORIGINAL ARTICLE egl‑4 modulates electroconvulsive seizure duration in C. elegans Monica G. Risley1,2 · Stephanie P. Kelly1,2 · Justin Minnerly1,2 · Kailiang Jia1,2 · Ken …
Modulating Behavior in C. elegans Using Electroshock and Antiepileptic Drugs
Type: Text
Year: 2016, 2016
Member of: FAU College Collections
Contributors: Brock Grill, Kailiang Jia, Ken Dawson- Scully, Monica G. Risley, Stephanie P. Kelly
Publisher: PLoS ONE
Description: The microscopic nematode Caenorhabditis elegans has emerged as a valuable model for understanding the molecular and cellular basis of neurological disorders. The worm offers important physiological similarities to mammalian models such as conserved neuron morphology, ion channels, and neurotransmitters. While a wide-array of behavioral assays are available in C. elegans, an assay for electroshock… more
Full Text: RESEARCH ARTICLE Modulating Behavior in C. elegans Using Electroshock and Antiepileptic Drugs Monica G. Risley1☯, Stephanie P. Kelly1☯, Kailiang Jia1, Brock Grill2, Ken DawsonScully1* 1 Department of Biological Sciences, Florida Atlantic University, Boca …