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Interrogating the Spatiotemporal Landscape of Neuromodulatory GPCR Signaling by Real-Time Imaging of cAMP in Intact Neurons and Circuits

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Type: Text
Year: 2018, 2018
Member of: FAU College Collections
Contributors: Brian S. Muntean, Caitlin Johnston, Courtney M. MacMullen, Hideki Iwamoto, Kirill A. Martemyanov, Maria T. Dao, Randy D. Blakely, Ronald L. Davis, Stefano Zucca
Publisher: Cell Press
Description: Modulation of neuronal circuits is key to information processing in the brain. The majority of neuromodulators exert their effects by activating G-proteincoupled receptors (GPCRs) that control the production of second messengers directly impacting cellular physiology. How numerous GPCRs integrate neuromodulatory inputs while accommodating diversity of incoming signals is poorly understood… more
Full Text: Resource Interrogating the Spatiotemporal Landscape of Neuromodulatory GPCR Signaling by Real-Time Imaging of cAMP in Intact Neurons and Circuits Graphical Abstract Authors Brian S. Muntean, Stefano Zucca, Courtney M. MacMullen, ..., Randy D. Blakely, …

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