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Organotin Polyethers as Biomaterials

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Type: Text
Year: 2009, 2009
Member of: FAU College Collections
Contributors: Carraher, Charles E., Roner, Michael R.
Description: Organotin polyethers are easily synthesized employing interfacial polymerization systems involving the reaction of hydroxyl-containing Lewis bases and organotin halides. A wide variety of organotin-containing polymeric products have been synthesized including those derived from natural and synthetic polymers such as lignin, xylan, cellulose, dextran, and poly(vinyl alcohol). Others have been… more
Full Text: Materials 2009, 2, 1558-1598; doi:10.3390/ma2041558 OPEN ACCESS materials ISSN 1996-1944 www.mdpi.com/journal/materials Review Organotin Polyethers as Biomaterials Charles E. Carraher Jr. 1,2,* and Michael R. Roner 3 1 2 3 Florida Atlantic University, …

Antiviral Activity of Metal-Containing Polymers—Organotin and Cisplatin-Like Polymers

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Type: Text
Year: 2011, 2011
Member of: FAU College Collections
Contributors: Barot, Girish, Carraher, Charles E., Roner, Michael R., Shahi, Kimberly
Description: Polymers containing platinum and to a lesser extent tin, have repeatedly demonstrated antitumor activity in vitro and in vivo against a variety of cell and tumor types. The mechanisms responsible for the antitumor activity include inducing a delay in cell proliferation and sister chromatid exchanges blocking tumor growth. As most DNA and some RNA viruses require, and even induce, infected cells… more
Full Text: Materials 2011, 4, 991-1012; doi:10.3390/ma4060991 OPEN ACCESS materials ISSN 1996-1944 www.mdpi.com/journal/materials Review Antiviral Activity of Metal-Containing Polymers—Organotin and Cisplatin-Like Polymers Michael R. Roner 1,*, Charles E. Carraher, …

Ability of Group IVB metallocene polyethers containing dienestrol to arrest the growth of selected cancer cell lines

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Type: Text
Year: 2009, 2009
Member of: FAU College Collections
Contributors: Ashida, Yuki, Barot, Girish, Carraher, Charles E., Roner, Michael R., Shahi, Kimberly
Full Text: FAU Institutional Repository http://purl.fcla.edu/fau/fauir This paper was submitted by the faculty of FAU’s Department of Chemistry and Biochemistry, Charles E. Schmidt College of Science Notice: This manuscript is available at …

Structural Consideration in Designing Organotin Polyethers to Arrest the Growth of Breast Cancer Cells In Vitro

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Type: Text
Year: 2011, 2011
Member of: FAU College Collections
Contributors: Barot, Girish, Carraher, Charles E., Roner, Michael R., Shahi, Kimberly
Description: The ability to inhibit cancer is inherent in organotin materials yet the structural relationships that regulate/direct this activity remains unknown. We measured antitumor activity using a matched pair of cell lines MDA-MB-231 cells that are estrogen-independent, estrogen receptor negative and MCF-7 cells, a cell line that is estrogen receptor (ER) positive. Those polyethers that contained a O-… more
Full Text: Materials 2011, 4, 801-815; doi:10.3390/ma4040801 OPEN ACCESS materials ISSN 1996-1944 www.mdpi.com/journal/materials Article Structural Consideration in Designing Organotin Polyethers to Arrest the Growth of Breast Cancer Cells In Vitro Charles E. …

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