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Glial Hsp70 Protects K+ Homeostasis in the Drosophila Brain during Repetitive Anoxic Depolarization

Type: Text

Year: 2011, 2011

Member of: FAU College Collections

Contributors: Armstrong, Gary A. B., Dawson-Scully, Ken, Krill, Jennifer L., Robertson, R. Meldrum, Roman, Gregg, Seroude, Laurent, Xiao, Chengfeng

Description: Neural tissue is particularly vulnerable to metabolic stress and loss of ion homeostasis. Repetitive stress generally leads to more permanent dysfunction but the mechanisms underlying this progression are poorly understood. We investigated the effects of energetic compromise in Drosophila by targeting the Na+/K+-ATPase. Acute ouabain treatment of intact flies resulted in subsequent repetitive… more

Full Text: Glial Hsp70 Protects K+ Homeostasis in the Drosophila Brain during Repetitive Anoxic Depolarization Gary A. B. Armstrong1*, Chengfeng Xiao1, Jennifer L. Krill2, Laurent Seroude1, Ken Dawson-Scully2, R. Meldrum Robertson1 1 Department of Biology, Queen’s …