FAU College Collections
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New Tools for Targeted Disruption of Cholinergic Synaptic Transmission in Drosophila melanogaster
Type: Text
Year: 2013, 2013
Member of: FAU College Collections
Contributors: Godenschwege, Tanja A., Heghinian, Mari D., Mari, Frank, McCabe, Brian D., Mejia, Monica
Description: Nicotinic acetylcholine receptors (nAChRs) are pentameric ligand-gated ion channels. The a7 subtype of nAChRs is involved
in neurological pathologies such as Parkinson’s disease, Alzheimer’s disease, addiction, epilepsy and autism spectrum
disorders. The Drosophila melanogaster a7 (Da7) has the closest sequence homology to the vertebrate a7 subunit and it can
form homopentameric receptors just… more
Full Text: New Tools for Targeted Disruption of Cholinergic Synaptic Transmission in Drosophila melanogaster Monica Mejia1, Mari D. Heghinian2, Frank Marı́2, Tanja A. Godenschwege3* 1 Department of Biological Sciences, Florida Atlantic University, Boca Raton, …
Transsynaptic Coordination of Synaptic Growth, Function, and Stability by the L1-Type CAM Neuroglian
Type: Text
Year: 2013, 2013
Member of: FAU College Collections
Contributors: Bellen, Hugo J., Boerner, Jana, Enneking, Eva-Maria, Godenschwege, Tanja A., Kudumala, Sirisha R., Moreno, Eliza, Pielage, Jan, Stephan, Raiko
Full Text: Transsynaptic Coordination of Synaptic Growth, Function, and Stability by the L1-Type CAM Neuroglian Eva-Maria Enneking1., Sirisha R. Kudumala2., Eliza Moreno1, Raiko Stephan1, Jana Boerner2, Tanja A. Godenschwege2*, Jan Pielage1* 1 Friedrich Miescher …
Differential Effects of Human L1CAM Mutations on Complementing Guidance and Synaptic Defects in Drosophila melanogaster
Type: Text
Year: 2013, 2013
Member of: FAU College Collections
Contributors: Freund, Julie, Godenschwege, Tanja A., Hortsch, Michael, Kudumala, Sirisha, Labrador, Juan-Pablo
Description: A large number of different pathological L1CAM mutations have been identified that result in a broad spectrum of
neurological and non-neurological phenotypes. While many of these mutations have been characterized for their effects on
homophilic and heterophilic interactions, as well as expression levels in vitro, there are only few studies on their biological
consequences in vivo. The single… more
Full Text: Differential Effects of Human L1CAM Mutations on Complementing Guidance and Synaptic Defects in Drosophila melanogaster Sirisha Kudumala1, Julie Freund1, Michael Hortsch2, Tanja A. Godenschwege1* 1 Department of Biological Sciences, Florida Atlantic …