FAU College Collections
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Antiviral Activity of Metal-Containing Polymers—Organotin and Cisplatin-Like Polymers
Type: Text
Year: 2011, 2011
Member of: FAU College Collections
Contributors: Barot, Girish, Carraher, Charles E., Roner, Michael R., Shahi, Kimberly
Description: Polymers containing platinum and to a lesser extent tin, have repeatedly demonstrated antitumor activity in vitro and in vivo against a variety of cell and tumor types. The mechanisms responsible for the antitumor activity include inducing a delay in cell proliferation and sister chromatid exchanges blocking tumor growth. As most DNA and some RNA viruses require, and even induce, infected cells… more
Full Text: Materials 2011, 4, 991-1012; doi:10.3390/ma4060991 OPEN ACCESS materials ISSN 1996-1944 www.mdpi.com/journal/materials Review Antiviral Activity of Metal-Containing Polymers—Organotin and Cisplatin-Like Polymers Michael R. Roner 1,*, Charles E. Carraher, …
Structural Consideration in Designing Organotin Polyethers to Arrest the Growth of Breast Cancer Cells In Vitro
Type: Text
Year: 2011, 2011
Member of: FAU College Collections
Contributors: Barot, Girish, Carraher, Charles E., Roner, Michael R., Shahi, Kimberly
Description: The ability to inhibit cancer is inherent in organotin materials yet the structural relationships that regulate/direct this activity remains unknown. We measured antitumor activity using a matched pair of cell lines MDA-MB-231 cells that are estrogen-independent, estrogen receptor negative and MCF-7 cells, a cell line that is estrogen receptor (ER) positive. Those polyethers that contained a O-… more
Full Text: Materials 2011, 4, 801-815; doi:10.3390/ma4040801 OPEN ACCESS materials ISSN 1996-1944 www.mdpi.com/journal/materials Article Structural Consideration in Designing Organotin Polyethers to Arrest the Growth of Breast Cancer Cells In Vitro Charles E. …