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Interrogating the Spatiotemporal Landscape of Neuromodulatory GPCR Signaling by Real-Time Imaging of cAMP in Intact Neurons and Circuits
Type: Text
Year: 2018, 2018
Member of: FAU College Collections
Contributors: Brian S. Muntean, Caitlin Johnston, Courtney M. MacMullen, Hideki Iwamoto, Kirill A. Martemyanov, Maria T. Dao, Randy D. Blakely, Ronald L. Davis, Stefano Zucca
Publisher: Cell Press
Description: Modulation of neuronal circuits is key to information
processing in the brain. The majority of neuromodulators
exert their effects by activating G-proteincoupled
receptors (GPCRs) that control the production
of second messengers directly impacting
cellular physiology. How numerous GPCRs integrate
neuromodulatory inputs while accommodating diversity
of incoming signals is poorly understood… more
Full Text: Resource Interrogating the Spatiotemporal Landscape of Neuromodulatory GPCR Signaling by Real-Time Imaging of cAMP in Intact Neurons and Circuits Graphical Abstract Authors Brian S. Muntean, Stefano Zucca, Courtney M. MacMullen, ..., Randy D. Blakely, …