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NR2C in the Thalamic Reticular Nucleus; Effects of the NR2C Knockout
Type: Text
Year: 2012, 2012
Member of: FAU College Collections
Contributors: Buonanno, Andres, Hoover, Walter B., Lisman, John E., Vertes, Robert P., Zhang, Yuchun, Zhang, Zhe
Description: NMDAR antagonists can evoke delta frequency bursting in the nucleus reticularis of the thalamus (nRT). The mechanism of
this oscillation was determined; antagonist blocks an NR2C-like conductance that has low Mg block at resting potential and
thus can contribute a resting inward current in response to ambient glutamate. Block of this current hyperpolarizes the cell,
deinactivating T-type Ca… more
Full Text: NR2C in the Thalamic Reticular Nucleus; Effects of the NR2C Knockout Yuchun Zhang1,2, Andres Buonanno3, Robert P. Vertes4, Walter B. Hoover4, John E. Lisman1,2* 1 Department of Biology, Brandeis University, Waltham, Massachusetts, United States of …