FAU College Collections
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The Roles of Substrate Thermal Stability and P2 and P1′ Subsite Identity on Matrix Metalloproteinase Triple-helical Peptidase Activity and Collagen Specificity
Type: Text
Year: 2006, 2006
Member of: FAU College Collections
Contributors: Brew, Keith, Cudic, Mare, Fields, Gregg B., Lauer-Fields, Janelle L., Minond, Dmitriy, Nagase, Hideaki, Overall, Christopher M., Pei, Duanqing, Visse, Robert
Full Text: THE JOURNAL OF BIOLOGICAL CHEMISTRY VOL. 281, NO. 50, pp. 38302–38313, December 15, 2006 © 2006 by The American Society for Biochemistry and Molecular Biology, Inc. Printed in the U.S.A. The Roles of Substrate Thermal Stability and P2 and P1ⴕ Subsite …
Bilayer Membrane Modulation of Membrane Type 1 Matrix Metalloproteinase (MT1-MMP) Structure and Proteolytic Activity
Type: Text
Year: 2016, 2016
Member of: FAU College Collections
Contributors: Amar, Sabrina, Cerofolini, Linda, Fields, Gregg B., Fragai, Marco, Lauer, Janelle L., Luchinat, Claudio, Martelli, Tommaso
Description: Cell surface proteolysis is an integral yet poorly understood physiological process. The present study
has examined how the pericellular collagenase membrane-type 1 matrix metalloproteinase (MT1-MMP)
and membrane-mimicking environments interplay in substrate binding and processing. NMR derived
structural models indicate that MT1-MMP transiently associates with bicelles and cells through… more
Full Text: www.nature.com/scientificreports OPEN received: 05 August 2015 accepted: 20 June 2016 Published: 13 July 2016 Bilayer Membrane Modulation of Membrane Type 1 Matrix Metalloproteinase (MT1-MMP) Structure and Proteolytic Activity Linda Cerofolini1, Sabrina …
The Mechanism by Which MYCN Amplification Confers an Enhanced Sensitivity to a PCNA-Derived Cell Permeable Peptide in Neuroblastoma Cells
Type: Text
Year: 2015, 2015
Member of: FAU College Collections
Contributors: Chu, Peiguo, Fields, Gregg B., Gu, Long, Hickey, Robert J., Kechichian, Steven, Lingeman, Robert, Liu, Zheng, Malkas, Linda H., McDaniel, Heather, Sandoval, John A., Yuan, Yate-Ching
Full Text: EBioMedicine 2 (2015) 1923–1931 Contents lists available at ScienceDirect EBioMedicine journal homepage: www.ebiomedicine.com Research Article The Mechanism by Which MYCN Amplification Confers an Enhanced Sensitivity to a PCNA-Derived Cell Permeable …
Development of a convenient peptide-based assay for lysyl hydroxylase
Type: Text
Year: 2007, 2007
Member of: FAU College Collections
Contributors: Brew, Keith, Cudic, Mare, Fields, Gregg B., Lauer-Fields, Janelle L., Patel, Deepak A.
Full Text: Development of a Convenient Peptide-Based Assay for Development of a Convenient Peptide-Based Assay for Lysyl Hydroxylase Lysyl Hydroxylase Mare Cudic,1 Deepak A. Patel,1 Janelle L. Lauer-Fields,1,2 Keith Brew,2 Gregg B. Fields1 1 Department of Chemistry …
Engineered Sarafotoxins as Tissue Inhibitor of Metalloproteinases-like Matrix Metalloproteinase Inhibitors
Type: Text
Year: 2007, 2007
Member of: FAU College Collections
Contributors: Brew, Keith, Cudic, Mare, Fields, Gregg B., Lauer-Fields, Janelle L., Mari, Frank, Wei, Shuo
Full Text: THE JOURNAL OF BIOLOGICAL CHEMISTRY VOL. 282, NO. 37, pp. 26948 –26955, September 14, 2007 © 2007 by The American Society for Biochemistry and Molecular Biology, Inc. Printed in the U.S.A. Engineered Sarafotoxins as Tissue Inhibitor of …