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The cell non-autonomous function of ATG-18 is essential for neuroendocrine regulation of Caenorhabditis elegans lifespan

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Type: Text
Year: 2017, 2017
Member of: FAU College Collections
Contributors: Jiuli Zhang, Justin Minnerly, Kailiang Jia, Thomas Parker, Tiffany Kaul
Publisher: Public Library of Science
Description: Restriction of dietary food without malnutrition robustly extends lifespan in more than twenty species. It was also reported that fruit flies (Drosophila melanogaster) deficient in olfactory function live longer and that the longevity induced by food restriction is partially due to decreased olfaction. These observations suggest food assimilation through the gastrointestinal tract and food… more
Full Text: RESEARCH ARTICLE The cell non-autonomous function of ATG-18 is essential for neuroendocrine regulation of Caenorhabditis elegans lifespan Justin Minnerly, Jiuli Zhang, Thomas Parker, Tiffany Kaul, Kailiang Jia* Department of Biological Sciences, Florida …

Intestinal autophagy activity is essential for host defense against Salmonella typhimurium infection in Caenorhabditis elega

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Type: Text
Year: 2014, 2014
Member of: FAU College Collections
Contributors: Alexander Curt, Jiuli Zhang, Justin Minnerly, Kailiang Jia
Publisher: Elsevier
Description: Salmonella typhimurium infects both intestinal epithelial cells and macrophages. Autophagy is a lysosomal degradation pathway that is present in all eukaryotes. Autophagy has been reported to limit the Salmonella replication in Caenorhabditis elegans and in mammals. However, it is unknown whether intestinal autophagy activity plays a role in host defense against Salmonella infection in C.… more
Full Text: Developmental and Comparative Immunology 45 (2014) 214–218 Contents lists available at ScienceDirect Developmental and Comparative Immunology journal homepage: www.elsevier.com/locate/dci Short communication Intestinal autophagy activity is essential for …

egl‑4 modulates electroconvulsive seizure duration in C. elegans

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Type: Text
Year: 2018, 2018
Member of: FAU College Collections
Contributors: Justin Minnerly, Kailiang Jia, Ken Dawson‑Scully, Monica G. Risley, Stephanie P. Kelly
Publisher: Springer Nature
Description: Increased neuronal excitability causes seizures with debilitating symptoms. Effective and noninvasive treatments are limited for easing symptoms, partially due to the complexity of the disorder and lack of knowledge of specific molecular faults. An unexplored, novel target for seizure therapeutics is the cGMP/protein kinase G (PKG) pathway, which targets downstream K+ channels, a mechanism… more
Full Text: Invertebrate Neuroscience (2018) 18:8 https://doi.org/10.1007/s10158-018-0211-9 ORIGINAL ARTICLE egl‑4 modulates electroconvulsive seizure duration in C. elegans Monica G. Risley1,2 · Stephanie P. Kelly1,2 · Justin Minnerly1,2 · Kailiang Jia1,2 · Ken …

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