FAU College Collections
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The cell non-autonomous function of ATG-18 is essential for neuroendocrine regulation of Caenorhabditis elegans lifespan
Type: Text
Year: 2017, 2017
Member of: FAU College Collections
Contributors: Jiuli Zhang, Justin Minnerly, Kailiang Jia, Thomas Parker, Tiffany Kaul
Publisher: Public Library of Science
Description: Restriction of dietary food without malnutrition robustly extends lifespan in more than
twenty species. It was also reported that fruit flies (Drosophila melanogaster) deficient in
olfactory function live longer and that the longevity induced by food restriction is partially
due to decreased olfaction. These observations suggest food assimilation through the gastrointestinal
tract and food… more
Full Text: RESEARCH ARTICLE The cell non-autonomous function of ATG-18 is essential for neuroendocrine regulation of Caenorhabditis elegans lifespan Justin Minnerly, Jiuli Zhang, Thomas Parker, Tiffany Kaul, Kailiang Jia* Department of Biological Sciences, Florida …
Aberrant Autolysosomal Regulation Is Linked to The Induction of Embryonic Senescence: Differential Roles of Beclin 1 and p53 in Vertebrate Spns1 Deficien
Type: Text
Year: 2014, 2014
Member of: FAU College Collections
Contributors: Christopher E. Carr, Daniel J. Klionsky, Jennifer L. Johnson, Jie Qi, Kailiang Jia, Matthew Gill, Patrick Kobler, Peter E. Bayliss, Sergio D. Catz, Shanshan Lian, Sujay Guha, Tomoyuki Sasaki
Publisher: Public Library of Science
Description: Spinster (Spin) in Drosophila or Spinster homolog 1 (Spns1) in vertebrates is a putative lysosomal H+-carbohydrate
transporter, which functions at a late stage of autophagy. The Spin/Spns1 defect induces aberrant autolysosome formation that leads to embryonic senescence and accelerated aging symptoms, but little is known about the mechanisms leading to the pathogenesis in vivo. Beclin 1 and p53… more
Full Text: Aberrant Autolysosomal Regulation Is Linked to The Induction of Embryonic Senescence: Differential Roles of Beclin 1 and p53 in Vertebrate Spns1 Deficiency Tomoyuki Sasaki1, Shanshan Lian1, Jie Qi1¤, Peter E. Bayliss2, Christopher E. Carr3, Jennifer L. …