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Patterns of Subnet Usage Reveal Distinct Scales of Regulation in the Transcriptional Regulatory Network of Escherichia coli

Type: Text

Year: 2010, 2010

Member of: FAU College Collections

Contributors: Babu, M. Madan, Hütt, Marc-Thorsten, Liebovitch, Larry S., Marr, Carsten, Theis, Fabian J.

Description: The set of regulatory interactions between genes, mediated by transcription factors, forms a species’ transcriptional regulatory network (TRN). By comparing this network with measured gene expression data, one can identify functional properties of the TRN and gain general insight into transcriptional control. We define the subnet of a node as the subgraph consisting of all nodes topologically… more

Full Text: Patterns of Subnet Usage Reveal Distinct Scales of Regulation in the Transcriptional Regulatory Network of Escherichia coli Carsten Marr1*, Fabian J. Theis1,2, Larry S. Liebovitch3, Marc-Thorsten Hütt4 1 Institute for Bioinformatics and Systems Biology, …