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egl‑4 modulates electroconvulsive seizure duration in C. elegans
Type: Text
Year: 2018, 2018
Member of: FAU College Collections
Contributors: Justin Minnerly, Kailiang Jia, Ken Dawson‑Scully, Monica G. Risley, Stephanie P. Kelly
Publisher: Springer Nature
Description: Increased neuronal excitability causes seizures with debilitating symptoms. Effective and noninvasive treatments are limited
for easing symptoms, partially due to the complexity of the disorder and lack of knowledge of specific molecular faults. An
unexplored, novel target for seizure therapeutics is the cGMP/protein kinase G (PKG) pathway, which targets downstream
K+
channels, a mechanism… more
Full Text: Invertebrate Neuroscience (2018) 18:8 https://doi.org/10.1007/s10158-018-0211-9 ORIGINAL ARTICLE egl‑4 modulates electroconvulsive seizure duration in C. elegans Monica G. Risley1,2 · Stephanie P. Kelly1,2 · Justin Minnerly1,2 · Kailiang Jia1,2 · Ken …