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Intestinal autophagy activity is essential for host defense against Salmonella typhimurium infection in Caenorhabditis elega

Type: Text

Year: 2014, 2014

Member of: FAU College Collections

Contributors: Alexander Curt, Jiuli Zhang, Justin Minnerly, Kailiang Jia

Publisher: Elsevier

Description: Salmonella typhimurium infects both intestinal epithelial cells and macrophages. Autophagy is a lysosomal degradation pathway that is present in all eukaryotes. Autophagy has been reported to limit the Salmonella replication in Caenorhabditis elegans and in mammals. However, it is unknown whether intestinal autophagy activity plays a role in host defense against Salmonella infection in C.… more

Full Text: Developmental and Comparative Immunology 45 (2014) 214–218 Contents lists available at ScienceDirect Developmental and Comparative Immunology journal homepage: www.elsevier.com/locate/dci Short communication Intestinal autophagy activity is essential for …