FAU Undergraduate Student Research
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Selected TLR Agonists Act in Synergy to Reprogram DC-NK Cross-talk and Generate Effector T cells in Nicotinic Environment
Type: Text
Year: 2016, 2016, 2016, 2016
Member of: FAU Undergraduate Student Research
Contributors: Abu-Nuwar, Emily, Nouri-Shirazi, Mahyar, Tamjidi, Saba
Publisher: Florida Atlantic University
Description: The magnitude of immune responses to vaccination
is a critical factor in determining protection from diseases.
We reported that nicotine disrupts the properties
of DCs that are pivotal in the initiation of immune
response to vaccines. Here we investigated whether
TLR agonist(s) could overcome the effects of nicotine
on human DC and DC-NK cross-talk essential
for effector T cell generation… more
Full Text: Selected TLR agonists act in synergy to reprogram DC-NK cross-talk and generate effector T cells in nicotinic environment Emily Abu-Nuwar , Saba Tamjidi, and Dr. Nouri-Shirazi College of Medicine, Florida Atlantic University Figure 1 Abstract The …