Florida Atlantic University Patents
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GFAP-Based Gene Therapy for Treatment of Retinal Diseases, 2008
Type: Text
Year: 2008, 2008, 2008, 2008
Member of: Florida Atlantic University Patents
Contributors: Blanks, Janet C., Dorey, C. Kathleen
Publisher: Florida Atlantic University
Description: Compositions and methods for reducing neovascularization.
Purified nucleic acid constructs and vectors encoding an antiangiogenic
protein operably linked to a GFAP promoter. Vectors
can include at least one hypoxia regulated element,
enhancer element and silencer element. Gene therapy methods
for reducing, delaying or preventing neovascularization
based on the nucleic acid constructs and vectors.
Full Text: 111111 1111111111111111111111111111111111111111111111111111111111111111111111111111 US 20080305083Al United States c12) Patent Application Publication (19) DOREY et al. (54) GFAP-BASED GENE THERAPY FOR TREATMENT OF RETINAL DISEASES (75) Inventors: C. …