Florida Atlantic University Patents
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Compositions and Methods for Treating Neural Anoxia and Spreading Depression, 2009
Type: Text
Year: 2009, 2009, 2009, 2009
Member of: Florida Atlantic University Patents
Contributors: Dawson-Scully, Ken, Robertson, R. Meldrum
Publisher: Florida Atlantic University
Description: Compositions and methods for protecting neural tissue (e.g.,
neurons) from anoxia and spreading depression (SD) involve
inhibiting the cGMP-dependent protein kinase (PKG) pathway.
It was discovered that the PKG pathway plays a crucial
role in regulating SD and tolerance to anoxia in the central
nervous system (CNS). Inhibition of the PKG pathway
greatly reduces SD and increases tolerance to… more
Full Text: 111111 1111111111111111111111111111111111111111111111111111111111111111111111111111 US 20090124558Al United States c12) Patent Application Publication (19) Dawson-Scully et al. (54) (75) COMPOSITIONS AND METHODS FOR TREATING NEURAL ANOXIA AND SPREADING …