The chromatographic properties of Octadecylsilica (ODS), Octadecylalumina (ODA), Polybutadiene coated alumina (PBD), Styrene-divinylbenzene copolymer (ACT-1) were investigated to evaluate Octanol-Water partition coefficient, log P, using a correlation method of High Performance Liquid Chromatographic (HPLC) capacity factor, k', and literature partition coefficient values. This study revealed the superior chromatographic characteristics of ODA material and its potential for the evaluation of log P values of organic compounds, in particular, bases. The log P(HPLC) values evaluated using the log k'-log P regression equation obtained from a set of standards on ODA appeared to be accurate. These values matched with the theoretical calculations supporting the accuracy of the HPLC method.