Metabolites from the Marine-Derived Fungus Chromocleista sp. Isolated from a Deep-Water Sediment Sample Collected in the Gulf of Mexico

Member of
HBOI Faculty Contributions
Contributors
Park, Young Chul
Gunasekera, Sarath P.
Lopez, Jose V.
McCarthy, Peter J.
Wright, Amy E.
Publisher
American Chemical Society and American Society of Pharmacognosy.
Date Issued
2006
Note

As part of our ongoing chemical investigation of biologically active metabolites from marine fungi, three new compounds, p-hydroxyphenopyrrozin (1) and diketopiperazines (3, 4), have been isolated from the marine-derived fungus Chromocleista sp. In addition, the fungus gave the known compound phenopyrrozin (2), four known diketopiperazines (6-9), N-acetyltryptamine (10), and agathic acid (11). Another new diketopiperazine (5) was separated and identified as a decomposition product of 3 and 4. The structures of the new metabolites were determined on the basis of mass spectroscopy, NMR experiments, and derivatization methods.

Language
English
Type
Text
Genre
article
Extent
6 p.
Subject (Topical)
Metabolites
Fungal metabolites
Marine fungi
X-ray crystallography
Marine sediments
Identifier
3164115
Additional Information
As part of our ongoing chemical investigation of biologically active metabolites from marine fungi, three new compounds, p-hydroxyphenopyrrozin (1) and diketopiperazines (3, 4), have been isolated from the marine-derived fungus Chromocleista sp. In addition, the fungus gave the known compound phenopyrrozin (2), four known diketopiperazines (6-9), N-acetyltryptamine (10), and agathic acid (11). Another new diketopiperazine (5) was separated and identified as a decomposition product of 3 and 4. The structures of the new metabolites were determined on the basis of mass spectroscopy, NMR experiments, and derivatization methods.
This document is the accepted manuscript version of a published work that appeared in final form in Journal of Natural Products after peer review and technical editing by the publisher. To access the final edited and published work see http://dx.doi.org/10.1021/np058113p. This article may be cited as: Park, Y. C., Gunasekera, S. P., Lopez, J. V., McCarthy, P. J. & Wright, A. E. (2006). Metabolites from the Marine-Derived Fungus Chromocleista sp. Isolated from a Deep-Water Sediment Sample Collected in the Gulf of Mexico. Journal of Natural Products, 69(4), 580-584.
Florida Atlantic University. Harbor Branch Oceanographic Institute contribution #1625.
Date Backup
2006
Date Text
2006
DOI
10.1021/np058113p
Date Issued (EDTF)
2006
Extension


FAU
FAU
admin_unit="FAU01", ingest_id="ing9359", creator="creator:BCHANG", creation_date="2011-04-25 13:59:40", modified_by="super:FAUDIG", modification_date="2014-02-10 14:33:53"

IID
FADT3164115
Issuance
single unit
Person Preferred Name

Park, Young Chul

creator

Physical Description

pdf
6 p.
PURL
http://purl.flvc.org/FCLA/DT/3164115
Title Plain
Metabolites from the Marine-Derived Fungus Chromocleista sp. Isolated from a Deep-Water Sediment Sample Collected in the Gulf of Mexico
URL
http://purl.flvc.org/FCLA/DT/3164115
Origin Information

American Chemical Society and American Society of Pharmacognosy.
2006
single unit
Title
Metabolites from the Marine-Derived Fungus Chromocleista sp. Isolated from a Deep-Water Sediment Sample Collected in the Gulf of Mexico
Other Title Info

Metabolites from the Marine-Derived Fungus Chromocleista sp. Isolated from a Deep-Water Sediment Sample Collected in the Gulf of Mexico