Microcolins A and B, new immunosuppressive peptides from the blue-green alga Lyngba majuscula

Microcolin A [l] and microcolin B [2] are new immunosuppressive lipopeptides isolated from a Venezuelan sample of the blue-green alga Lyngbya majuscula. The microcolins are potent inhibitors of the murine mixed lymphocyte response and murine P-388 leukemia in vitro. Isolation and structure elucidation of 1 and 2 by nmr, mass spectral, and chemical methods are described.

This document is the accepted manuscript version of a published work that appeared in final form in Journal of Natural Products after peer review and technical editing by the publisher. To access the final edited and published work see http://dx.doi.org/10.1021/np50083a009. This article may be cited as: Koehn, F. E., Longley, R. E., & Reed, J. K. (1992). Microcolins A and B, new immunosuppressive peptides from the blue-green alga Lyngba majuscula. Journal of Natural Products, 55(5), 613-619. doi:10.1021/np50083a009

Florida Atlantic University. Harbor Branch Oceanographic Institute contribution #895.