Naturally mosaic operons for secondary metabolite biosynthesis: variability and putative horizontal transfer of discrete catalytic domains of the epothilone polyketide synthase locus

This study emphasizes the use of several lines of concordant evidence (phylogenetics, base composition, transposon sequences) to infer the evolutionary history of particular gene and enzyme sequences, and the results support the idea that genes coding for adaptive traits, e.g. defensive natural products, may be prone to transposition between divergent prokaryotic taxa and genomes.

This manuscript is an author version with the final publication available at http://www.springerlink.com and may be cited as: Lopez, J. V. (2003). Naturally mosaic operons for secondary metabolite biosynthesis: variability and putative horizontal transfer of discrete catalytic domains of the epothilone polyketide synthase locus. Molecular Genetics and Genomics, 270(9), 420-431.

Florida Atlantic University. Harbor Branch Oceanographic Institute contribution #1519.

Date Backup

2003

Date Text

2003

DOI

10.1007/s00438-003-0937-9

Date Issued (EDTF)

2003

Extension

FAU
FAU
admin_unit="FAU01", ingest_id="ing9619", creator="creator:BCHANG", creation_date="2011-05-20 15:45:06", modified_by="super:FAUDIG", modification_date="2014-02-10 14:39:54"

IID

FADT3166884

Issuance

single unit

Organizations

Attributed name: Harbor Branch Oceanographic Institute

Person Preferred Name

Lopez, Jose V.

creator

Physical Description

pdf
13 p.

PURL

http://purl.flvc.org/FCLA/DT/3166884

Title Plain

Naturally mosaic operons for secondary metabolite biosynthesis: variability and putative horizontal transfer of discrete catalytic domains of the epothilone polyketide synthase locus

URL

http://purl.flvc.org/FCLA/DT/3166884

Origin Information

Springer-Verlag
2003
single unit

Title

Naturally mosaic operons for secondary metabolite biosynthesis: variability and putative horizontal transfer of discrete catalytic domains of the epothilone polyketide synthase locus

Other Title Info

Naturally mosaic operons for secondary metabolite biosynthesis: variability and putative horizontal transfer of discrete catalytic domains of the epothilone polyketide synthase locus