A new bastadin from the sponge Psammaplysilla purpurea

A new bastadin 2 and the previously reported bastadins 5 [3], 7 [4], and 12 (formerly bastadin 9) [5] were isolated from the Verongid sponge Psammapplysilla purpurea collected in Pohnpei. Compound 2 is mildly cytotoxic against several cell lines and inhibits the enzymes topoisomerase II and dehydrofolate reductase.

This document is the accepted manuscript version of a published work that appeared in final form in Journal of Natural Products after peer review and technical editing by the publisher. To access the final edited and published work see http://dx.doi.org/10.1021/np50091a025. This article may be cited as: Carney, J. R., Scheuer, P. J., & Kelly-Borges, M. (1993). A new bastadin from the sponge Psammaplysilla purpurea. Journal of Natural Products, 56(1), 153-157. doi:10.1021/np50091a025

Florida Atlantic University. Harbor Branch Oceanographic Institute contribution #949.