Note
Thesis (M.A.)--Florida Atlantic University, 1981.
Member of
Contributors
Publisher
Florida Atlantic University
Date Issued
1981
Description
Rats with lesions of the ventromedial aspect of the internal
capsule in the vicinty of the entopeduncular nucleus (EP) showed a loss
of forelimb placing (chin, contact and visual) in the contralateral
limb. Spreading depression induced by instillation of KCl (25%) to the
cortex contralateral to the lesion brought back placing in the affected
limb and abolished placing in the normal limb. Within 24 hours the
pre-spreading depression state returned and the impaired limb no longer
placed while the normal limb recovered function. In contrast, KCl on
the ipsilateral cortex did not reinstate placing. These results
suggest that the loss of placing following lesions of the EP are due to
tonic inhibition from the cortex contralateral to the lesion. Sensory
summation was evident during the early recovery period when placing was
accomplished only if two kinds of stimuli were provided
simultaneously. Forelimb placing recovered to its pre-lesion state.
capsule in the vicinty of the entopeduncular nucleus (EP) showed a loss
of forelimb placing (chin, contact and visual) in the contralateral
limb. Spreading depression induced by instillation of KCl (25%) to the
cortex contralateral to the lesion brought back placing in the affected
limb and abolished placing in the normal limb. Within 24 hours the
pre-spreading depression state returned and the impaired limb no longer
placed while the normal limb recovered function. In contrast, KCl on
the ipsilateral cortex did not reinstate placing. These results
suggest that the loss of placing following lesions of the EP are due to
tonic inhibition from the cortex contralateral to the lesion. Sensory
summation was evident during the early recovery period when placing was
accomplished only if two kinds of stimuli were provided
simultaneously. Forelimb placing recovered to its pre-lesion state.
Language
Type
Form
Extent
53 p.
Subject (Topical)
Identifier
14078
Additional Information
Thesis (M.A.)--Florida Atlantic University, 1981.
Charles E. Schmidt College of Science
FAU Electronic Theses and Dissertations Collection
Date Backup
1981
Date Text
1981
Date Issued (EDTF)
1981
Extension
FAU
FAU
admin_unit="FAU01", ingest_id="ing1508", creator="staff:fcllz", creation_date="2007-07-19 02:04:21", modified_by="staff:fcllz", modification_date="2011-01-06 13:09:06"
IID
FADT14078
Issuance
monographic
Organizations
Attributed name: Florida Atlantic University
Attributed name: Charles E. Schmidt College of Science
Attributed name: Department of Psychology
Person Preferred Name
Kehoe, Priscilla
Graduate College
Physical Description
53 p.
application/pdf
Title Plain
REVERSAL OF FORELIMB PLACING DEFICITS WITH CORTICAL SPREADING DEPRESSION
Use and Reproduction
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Origin Information
1981
monographic
Boca Raton, FL
Florida Atlantic University
Physical Location
Florida Atlantic University Libraries
Place
Boca Raton, FL
Sub Location
Digital Library
Title
REVERSAL OF FORELIMB PLACING DEFICITS WITH CORTICAL SPREADING DEPRESSION
Other Title Info
REVERSAL OF FORELIMB PLACING DEFICITS WITH CORTICAL SPREADING DEPRESSION