Three new bromotyrosine derived metabolites of the sponge Psammaplysilla purpurea

Marine sponges of the order Verongida are often characterized by a wide range of bioactive bromotyrosine constituents (1,2). The large number of biosynthetically related compounds is due to chemical variations occurring in the side chain and/or aromatic ring of the tyrosine moiety. We now report the structures and in vitro bioactivity of aplysamines 3 [3], 4 [3], and 5 [4], which are related to aplysamine 2 [1].

This document is the accepted manuscript version of a published work that appeared in final form in Journal of Natural Products after peer review and technical editing by the publisher. To access the final edited and published work see http://dx.doi.org/10.1021/np50099a025. This article may be cited as: Jurek, J., Yoshida, W. Y., Scheuer, P. J., & Kelly-Borges, M. (1993). Three new bromotyrosine derived metabolites of the sponge Psammaplysilla purpurea. Journal of Natural Products, 56(9), 1609-1612. doi:10.1021/np50099a025

Florida Atlantic University. Harbor Branch Oceanographic Institute contribution #960.