Note
Includes bibliography.
Member of
Contributors
Publisher
Florida Atlantic University
Date Issued
2014
EDTF Date Created
2014
Description
A detailed dosimetric comparison between Inverse Planning by Simulated Annealing (IPSA) and Dose Points (DP) optimized treatment plans has been performed
for High Dose Rate (HDR) brachytherapy of skin lesions using Freiburg Flap applicator
in order to find out whether or not IPSA offers better clinical dosimetric outcomes for
lesions categorized into four different curvatures. Without compromising target coverage,
IPSA reduced the volume of Planning Target Volume (lesion) that received at least 125%
of the prescription dose on average by 41%. It also reduced the volume of the healthy
skin surrounding the lesion that receives at least 100% of the prescription dose on
average by 42%. IPSA did not show any advantage over DP in sparing normal structures
underlying the lesions treated. Although DP optimization algorithm has been regularly
used at Lynn Cancer Institute for HDR brachytherapy of skin lesions, recent upgrades in IPSA software have made IPSA more amenable to rapid treatment planning and therefore
IPSA can be used either in place of DP or as its alternative.
for High Dose Rate (HDR) brachytherapy of skin lesions using Freiburg Flap applicator
in order to find out whether or not IPSA offers better clinical dosimetric outcomes for
lesions categorized into four different curvatures. Without compromising target coverage,
IPSA reduced the volume of Planning Target Volume (lesion) that received at least 125%
of the prescription dose on average by 41%. It also reduced the volume of the healthy
skin surrounding the lesion that receives at least 100% of the prescription dose on
average by 42%. IPSA did not show any advantage over DP in sparing normal structures
underlying the lesions treated. Although DP optimization algorithm has been regularly
used at Lynn Cancer Institute for HDR brachytherapy of skin lesions, recent upgrades in IPSA software have made IPSA more amenable to rapid treatment planning and therefore
IPSA can be used either in place of DP or as its alternative.
Language
Type
Form
Extent
102 p.
Subject (Topical)
Identifier
FA00004285
Additional Information
Includes bibliography.
Thesis (M.S.)--Florida Atlantic University, 2014.
FAU Electronic Theses and Dissertations Collection
Date Backup
2014
Date Created Backup
2014
Date Text
2014
Date Created (EDTF)
2014
Date Issued (EDTF)
2014
Extension
FAU
IID
FA00004285
Organizations
Attributed name: Florida Atlantic University
Attributed name: Charles E. Schmidt College of Science
Attributed name: Department of Physics
Person Preferred Name
Ghebremichael, Bereket Tewolde
author
Graduate College
Physical Description
application/pdf
102 p.
Title Plain
Dosimetric comparison of inverse planning by simulated annealing (IPSA) and dose
points optimized treatment plans in high dose rate (HDR) brachytherapy of skin lesions using Freiburg flap applicator
points optimized treatment plans in high dose rate (HDR) brachytherapy of skin lesions using Freiburg flap applicator
Use and Reproduction
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http://rightsstatements.org/vocab/InC/1.0/
Origin Information
2014
2014
Florida Atlantic University
Boca Raton, Fla.
Physical Location
Florida Atlantic University Libraries
Place
Boca Raton, Fla.
Sub Location
Digital Library
Title
Dosimetric comparison of inverse planning by simulated annealing (IPSA) and dose
points optimized treatment plans in high dose rate (HDR) brachytherapy of skin lesions using Freiburg flap applicator
points optimized treatment plans in high dose rate (HDR) brachytherapy of skin lesions using Freiburg flap applicator
Other Title Info
Dosimetric comparison of inverse planning by simulated annealing (IPSA) and dose
points optimized treatment plans in high dose rate (HDR) brachytherapy of skin lesions using Freiburg flap applicator