An antiviral sesquiterpene hydroquinone from the marine sponge Strongylophora hartmani

A new sesquiterpene hydroquinone 1, which we call strongylin A, was isolated from the marine sponge Strongylophora hartmani. Its structure was determined through spectroscopic methods, including 2D-13C homonuclear correlation spectroscopy (INADEQUATE). Both 1 and its acetate derivative are active in in vitro assays against the P-388 tumor cell line and influenza strain PR-8.

This document is the accepted manuscript version of a published work that appeared in final form in Journal of Natural Products after peer review and technical editing by the publisher. To access the final edited and published work see http://dx.doi.org/10.1021/np50076a032. This article may be cited as: Wright, A. E., Rueth, S. A., & Cross, S. S. (1991). An antiviral sesquiterpene hydroquinone from the marine sponge Strongylophora hartmani. Journal of Natural Products, 54(4), 1108-1111. doi:10.1021/np50076a032

Florida Atlantic University. Harbor Branch Oceanographic Institute contribution #849.