New cytotoxic acridine alkaloids from two deep water marine sponges of the family Pachastrellidae

Member of
HBOI Faculty Contributions
Contributors
Gunawardana, G. P.
Kohmoto, S.
Burres, N. S.
Publisher
Elsevier
Date Issued
1989
Note

Fused ring alkaloids having the pyridol[4,3,2-mn]acridine skeleton comprise a new class of marine natural products.1a–h Their biological activity1e and challenging structure elucidation make them an interesting group of compounds. In this paper we report the identification of four newcytotoxic and structurally related alkaloids: nordercitin (1), dercitamine (2), dercitamide (3), and cyclodercitin (4).

Language
English
Type
Text
Genre
article
Extent
5 p.
Subject (Topical)
Sponges
Acridines
Alkaloids
Cytotoxins
Identifier
3353842
Additional Information
Fused ring alkaloids having the pyridol[4,3,2-mn]acridine skeleton comprise a new class of marine natural products.1a–h Their biological activity1e and challenging structure elucidation make them an interesting group of compounds. In this paper we report the identification of four newcytotoxic and structurally related alkaloids: nordercitin (1), dercitamine (2), dercitamide (3), and cyclodercitin (4).
The final published version of this manuscript is available at http://www.sciencedirect.com/science/journal/00404039 and may be cited as: Gunawardana, G. P., Kohmoto, S., & Burres, N. S. (1989). New cytotoxic acridine alkaloids from two deep water marine sponges of the family Pachastrellidae. Tetrahedron Letters, 30(33), 4359-4362. doi:10.1016/S0040-4039(00)99360-2
Florida Atlantic University. Harbor Branch Oceanographic Institute contribution #723.
Date Backup
1989
Date Text
1989
DOI
10.1016/S0040-4039(00)99360-2
Date Issued (EDTF)
1989
Extension


FAU
FAU
admin_unit="FAU01", ingest_id="ing13951", creator="creator:BCHANG", creation_date="2012-10-29 12:27:44", modified_by="super:FAUDIG", modification_date="2014-02-07 12:36:26"

IID
FADT3353842
Issuance
single unit
Organizations
Attributed name: Harbor Branch Oceanographic Institute
Person Preferred Name

Gunawardana, G. P.

creator

Physical Description

pdf
5 p.
PURL
http://purl.flvc.org/FCLA/DT/3353842
Title Plain
New cytotoxic acridine alkaloids from two deep water marine sponges of the family Pachastrellidae
URL
http://purl.flvc.org/FCLA/DT/3353842
Origin Information

Elsevier
1989
single unit
Title
New cytotoxic acridine alkaloids from two deep water marine sponges of the family Pachastrellidae
Other Title Info

New cytotoxic acridine alkaloids from two deep water marine sponges of the family Pachastrellidae