Note
Charles E. Schmidt College of Science
Member of
Contributors
Publisher
Florida Atlantic University
Date Issued
1992
Description
The performance of several alkyl-bonded alumina-based stationary phases was evaluated by comparing the separation of synthetic octapeptide and polypeptide mixtures and tryptic digests of larger proteins. These phases were of differing pore diameter, alkyl chain length modification and particle shape and size. The separations were compared to standard silica phases. The narrow pore octadecyl bonded alumina phase outperformed the other alumina and silica phases in terms of separation efficiency and mobile phase resistance. Superior performance is attributed to the enhanced solute mass transfer properties and the unique morphology of the microplatelet alumina particles. The mechanism of separation gradually changes with increasing size of the peptide.
Language
Type
Form
Extent
157 p.
Subject (Topical)
Identifier
14831
Additional Information
Charles E. Schmidt College of Science
Thesis (M.S.)--Florida Atlantic University, 1992.
Date Backup
1992
Date Text
1992
Date Issued (EDTF)
1992
Extension
FAU
FAU
admin_unit="FAU01", ingest_id="ing1508", creator="staff:fcllz", creation_date="2007-07-19 03:13:46", modified_by="staff:fcllz", modification_date="2011-01-06 13:09:14"
IID
FADT14831
Issuance
monographic
Organizations
Attributed name: Florida Atlantic University
Attributed name: Department of Chemistry and Biochemistry
Attributed name: Charles E. Schmidt College of Science
Person Preferred Name
Ramdial, Nirmala Debra-Ann
Graduate College
Physical Description
157 p.
application/pdf
Title Plain
Comparison of alkyl-bonded alumina-based stationary phases for peptide separation by high performance liquid chromatography
Use and Reproduction
Copyright © is held by the author, with permission granted to Florida Atlantic University to digitize, archive and distribute this item for non-profit research and educational purposes. Any reuse of this item in excess of fair use or other copyright exemptions requires permission of the copyright holder.
http://rightsstatements.org/vocab/InC/1.0/
Origin Information
1992
monographic
Boca Raton, Fla.
Florida Atlantic University
Physical Location
Florida Atlantic University Libraries
Place
Boca Raton, Fla.
Sub Location
Digital Library
Title
Comparison of alkyl-bonded alumina-based stationary phases for peptide separation by high performance liquid chromatography
Other Title Info
Comparison of alkyl-bonded alumina-based stationary phases for peptide separation by high performance liquid chromatography