This thesis refers to a research addressing the use of binary representation of the DNA for the purpose of developing useful algorithms for Bioinformatics. Pertinent studies address the use of a binary form of the DNA base chemicals in information-theoretic base so as to identify symmetry between DNA and complementary DNA. This study also refers to "fuzzy" (codon-noncodon) considerations in delinating codon and noncodon regimes in a DNA sequences. The research envisaged further includes a comparative analysis of the test results on the aforesaid efforts using different statistical metrics such as Hamming distance Kullback-Leibler measure etc. the observed details supports the symmetry aspect between DNA and CDNA strands. It also demonstrates capability of identifying non-codon regions in DNA even under diffused (overlapped) fuzzy states.