Two antitumor macrodiolides, bistheonellides A and B, were isolated from amarinesponge sp. Bistheonellide A was found to be identical with misakinolideA, whose structure has been revised from the previously proposed monomeric macrolide (3) to the dimeric macrodiolide (1). Similarly, bistheonellide B was deduced to be the related structure2.
The final published version of this manuscript is available at http://www.sciencedirect.com/science/journal/00404039 and may be cited as: Kato, Y., Fusetani, N., Matsunaga, S., & Hashimoto, K., & Sakai, R., Higa, T., & Kashman, Y. (1987). Antitumor macrodiolides isolated from a marine sponge Theonella sp.: structure revision of misakinolide A. Tetrahedron Letters, 28(49), 6225-6228. doi:10.1016/S0040-4039(00)61853-1
Florida Atlantic University. Harbor Branch Oceanographic Institute contribution #649.