Cytotoxin production by a marine Lyngbya strain (cyanobacterium) in a large-scale laboratory bioreactor

A cytotoxic compound was produced by the marine cyanobacterium Lyngbya sp. Pearl strain in large laboratory-scale batch cultures. Adsorption and fractionation of methanol extracts with reverse phase (C-18) cartridges provided a rapid method for removal of bioassay interference from salts, biopolymers and pigments and concentration of the cytotoxic principles. Cytotoxicity to the murine leukemia cell line P-388 was produced in two cycles coinciding with the initiation of exponential growth and again during the late exponential growth phase.

This manuscript is an author version with the final publication available at http://www.springerlink.com and may be cited as: Armstrong, J. E., Janda, K. E., Alvarado, B., & Wright, A. E. (1991). Cytotoxin production by a marine Lyngbya strain (cyanobacterium) in a large-scale laboratory bioreactor. Journal of Applied Phycology, 3(3), 277-282. doi:10.1007/BF00003586

Florida Atlantic University. Harbor Branch Oceanographic Institute contribution #853.

Date Backup

1991

Date Text

1991

DOI

10.1007/BF00003586

Date Issued (EDTF)

1991

Extension

FAU
FAU
admin_unit="FAU01", ingest_id="ing12184", creator="creator:BCHANG", creation_date="2012-02-27 17:44:47", modified_by="super:FAUDIG", modification_date="2014-02-13 12:40:10"

IID

FADT3333194

Issuance

single unit

Person Preferred Name

Armstrong, J. E.

creator

Physical Description

pdf
7 p.

PURL

http://purl.flvc.org/FCLA/DT/3333194

Title Plain

Cytotoxin production by a marine Lyngbya strain (cyanobacterium) in a large-scale laboratory bioreactor

URL

http://purl.flvc.org/FCLA/DT/3333194

Origin Information

Springer
1991
single unit

Title

Cytotoxin production by a marine Lyngbya strain (cyanobacterium) in a large-scale laboratory bioreactor

Other Title Info

Cytotoxin production by a marine Lyngbya strain (cyanobacterium) in a large-scale laboratory bioreactor