A new bicyclic guanidine alkaloid, Sch 575948, from amarine sponge, Ptilocaulis spiculifer

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Japan Antibiotics Research Association
Date Issued
2003
Note

In the course of our continuing search for novel antimicrobial
agents, we have isolated a new antibacterial
compound Sch 575948 (1) along with a known alkaloid
ptilomycalin A (2) from a marine sponge Ptilocaulis
spiculifer (or Crambe crambe). Sch 575948 was identified
as a bicyclic bis-guanidine type of alkaloid, a homolog of
crambcscin A (or crambine A (3)), identified as a major
component of the homolog complex.

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Type
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Extent
4 p.
Identifier
FA00007361
Additional Information
In the course of our continuing search for novel antimicrobial
agents, we have isolated a new antibacterial
compound Sch 575948 (1) along with a known alkaloid
ptilomycalin A (2) from a marine sponge Ptilocaulis
spiculifer (or Crambe crambe). Sch 575948 was identified
as a bicyclic bis-guanidine type of alkaloid, a homolog of
crambcscin A (or crambine A (3)), identified as a major
component of the homolog complex.
Florida Atlantic University. Harbor Branch Oceanographic Institute contribution 1556
This manuscript is an author version with the
final publication available and may be cited as: Yang, S. W., Chan, T. M., Pomponi, S. A., Chen, G.,
Wright, A. E., Patel, M., . . . Chu, M. (2003). A new bicyclic guanidine alkaloid, Sch 575948, from a
marine sponge, Ptilocaulis spiculifer. The Journal of Antibiotics, 56(11), 970-972.
Date Backup
2003
Date Text
2003
DOI
10.7164/antibiotics.56.970
Date Issued (EDTF)
2003
Extension


FAU

IID
FA00007361
Organizations
Attributed name: Pomponi, Shirley A.
Person Preferred Name

Yang, Shu-Wei
Physical Description

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4 p.
Title Plain
A new bicyclic guanidine alkaloid, Sch 575948, from amarine sponge, Ptilocaulis spiculifer
Origin Information

2003
Japan Antibiotics Research Association

Tokyo, Japan

Place

Tokyo, Japan
Title
A new bicyclic guanidine alkaloid, Sch 575948, from amarine sponge, Ptilocaulis spiculifer
Other Title Info

A new bicyclic guanidine alkaloid, Sch 575948, from amarine sponge, Ptilocaulis spiculifer