Note
Thesis (M.S.)--Florida Atlantic University, 1988.
Member of
Contributors
Publisher
Florida Atlantic University
Date Issued
1988
Description
One of the most common chemotherapeutic drugs in use today is cis-DDP. While this substance has been found useful in the treatment of various malignant neoplasias, it also has many adverse side effects. Recently, polymeric cis-DDP analogs have been prepared using potassium tetrachloroplatinate and various diamines. Testing of these polymeric analogs has shown that some are biologically active while others are biologically inactive. The goal of this research was to investigate the possible reasons for the differences in biological activity which had been observed. The biological activity of the diamine components, the molecular weight of the polymers, and the degradation of the polymers were examined to determine if any of these properties of the polymers could be correlated to their biological activities.
Language
Type
Form
Extent
124 p.
Subject (Topical)
Identifier
14469
Additional Information
Thesis (M.S.)--Florida Atlantic University, 1988.
Charles E. Schmidt College of Science
FAU Electronic Theses and Dissertations Collection
Date Backup
1988
Date Text
1988
Date Issued (EDTF)
1988
Extension
FAU
FAU
admin_unit="FAU01", ingest_id="ing1508", creator="staff:fcllz", creation_date="2007-07-19 02:40:18", modified_by="staff:fcllz", modification_date="2011-01-06 13:09:10"
IID
FADT14469
Issuance
monographic
Organizations
Attributed name: Florida Atlantic University
Person Preferred Name
Brenner, Dora Lynn.
Graduate College
Physical Description
124 p.
Title Plain
Chemistry and biological activity of platinum (II) polyamines
Use and Reproduction
Copyright © is held by the author, with permission granted to Florida Atlantic University to digitize, archive and distribute this item for non-profit research and educational purposes. Any reuse of this item in excess of fair use or other copyright exemptions requires permission of the copyright holder.
http://rightsstatements.org/vocab/InC/1.0/
Origin Information
1988
monographic
Boca Raton, Fla.
Florida Atlantic University
Physical Location
Florida Atlantic University Libraries
Place
Boca Raton, Fla.
Sub Location
Digital Library
Title
Chemistry and biological activity of platinum (II) polyamines
Other Title Info
Chemistry and biological activity of platinum (II) polyamines