This thesis considers the relationship between scientific advances, identity formation, and literature in an early modern print culture. As medical theorists made their discoveries and defended their work they did so within the literary world; turning to the printed word to cultivate their personal identity and rebut dissenting colleagues. Subsequently, playwright William Shakespeare employed common medical knowledge within his plays. Twelfth Night presents male and female twins within the scope of a comedy that plays upon the issues of cross-dressing and mistaken sexual identity. During the Renaissance, it was believed that male and female seed was co-present in every person and through dominance a distinct sexual identity was developed. This thesis argues that while Shakespeare initially convoluted this by allowing one of the twins to cross-dress; he resolved the anatomical doubling by presenting both characters together on stage at the close of the play.

In an attempt to reduce runaway inflation, the Ecuadorian government froze citizens' checking and savings accounts for a year in March 1999. Nevertheless, Ecuador still experienced hyperinflation later that year. On January 9, 2000, Ecuador established dollarization as a desperate attempt to restore confidence in the economy. In order to test for dollarization's impact on economic growth, I employ an econometrics model with total factor productivity as the dependent variable. I then use dollarization as the independent variable of interest, and other control variables such as oil, and trade. The results reported in this paper suggest that dollarization has a significant positive impact on Ecuador's economic growth.

Phase-vanishing reactions are triphasic reactions that involve a reagent, a liquid perfluoroalkane, and a substrate. In a phase-vanishing reaction with PTFE (polytetrafluoroethylene) tape as the phase screen instead of a liquid perfluoroalkane, there is no limitation related to the density of a phase, and the denser phase can be in the top layer. Additionally, PTFE tape is inexpensive, easy to use, and reusable. In this work we qualitatively described PTFE tape's thickness, stretching characteristics, and permeability. We investigated the phase-vanishing PTFE method's usefulness both in known transformations and also in a novel nucleophile-assisting leaving group (NALG) reaction with menthol, thionyl bromide, and zirconium(IV) chloride. We successfully used PTFE tape as a phase screen in bromination, bromolactonization, esterification, chemiluminescence, and tandem bromination/esterification phase-vanishing reactions. We found that the PTFE tape is an effective phase screen and useful in performing a slow addition of a reagent.

Microelectromechanical systems (MEMS) accelerometers and gyroscopes are small scale sensors that measure changes in linear acceleration and rotational velocity, respectively. They are fabricated using electronic circuit techniques such as etching and deposition. MEMS motion sensors can be used in an Inertial Measurement Unit (IMU) that can be integrated with the Global Positioning System (GPS) to make a navigation system that is more accurate than each system alone. However, since MEMS-based IMUs are inherently noisy, we must overcome inaccuracies caused by the integration of random noise to find position. Accuracy can be increased by applying digital filters to the data before integration. Comparing the success of finite impulse response (FIR) filters and infinite impulse response (IIR) filters, we found that even though our highest order FIR filter yielded the most accurate position, it was limited by an offset bias in the accelerometer signal and a time delay in the determined position.

The education of profoundly intellectually disabled individuals requires identifying motivators to help them learn basic tasks and skills. When these individuals also suffer from Autism Spectrum Disorder, one promising method of therapy, multisensory therapy, has been shown to relax patients, facilitating the educational process. Relaxation drastically minimizes maladaptive behaviors such as repetitive movement (stereotypy) and self-injury, allowing the participant to learn efficiently. In this study, a multi-axis measure was developed to determine behavioral differences between an experimental group that underwent the therapy and a control group that performed a functional task in their classroom. Stereotypic behaviors were significantly reduced and gaze focus was enhanced within the therapy. The significance of these effects carried over when participants were returned to their classroom.

The two earliest grammars of the Castilian language are the Grammar of the Castilian Language by Antonio de Nebrija and the Dialogue of the Language by Juan de Valdâes. The former was published in 1492, a historically paramount year for Spain, while the latter was completed in 1535 but not published until two centuries later. Working with edited texts of both grammars, secondary sources regarding the lives of Nebrija and Valdâes, and information about the history of Spain, this thesis explores the linguistic substance of both works, evidence of the authors' personal attitudes and dispositions that influenced their works, and the political and social context surrounding all of these factors. The purpose of this investigation is to gain further insight into the Grammar and the Dialogue, as well as the history of Spain and the historical development of Castilian.

Aneuploid tumor cells have characteristically unstable genomes which can be caused by mitotic defects such as multipolar spindles. Multipolarity relies upon the presence of extra centrosomes to form. However, some cells, both cancerous and noncancerous are able to avoid the formation of multipolar spindles through centrosomal clustering. Previous research has shown that there are a large number of genes whose activity contributes to the clustering activity, making analysis of individual components of the process difficult. In order to better understand centrosomal clustering in cancer cells, we induced supernumerary centrosomes in a genomically normal cell line, RPE, to observe how the normal cells cope with extra centrosomes. Using colcemid to induce extra centrosomes in the RPE cell line, we observed an intact clustering mechanism in fixed cells. Further manipulation of the cells has allowed us to induce multipolarity in this cell line using various disrupters of cell-cycle checkpoint and dynein function.

The education of profoundly intellectually disabled individuals requires identifying motivators to help them learn basic tasks and skills. When these individuals also suffer from Autism Spectrum Disorder, one promising method of therapy, multisensory therapy, has been shown to relax patients, facilitating the educational process. Relaxation drastically minimizes maladaptive behaviors such as repetitive movement (stereotypy) and self-injury, allowing the participant to learn efficiently. In this study, a multi-axis measure was developed to determine behavioral differences between an experimental group that underwent the therapy and a control group that performed a functional task in their classroom. Stereotypic behaviors were significantly reduced and gaze focus was enhanced within the therapy. The significance of these effects carried over when participants were returned to their classroom.

In his article, "The Kentucky Fried Rat : Legends and Modem Society", Gary Alan Fine suggests that American society is a folk community in which urban legends play the role of negotiating changes in social structure and other aspects of daily life (Fine 2005). Fine's argument, however, is limiting in that it only considers urban legends within the United States and fails to encompass those from abroad. As such, this thesis expands Fine's original argument to a global scale by examining urban legends, crossculturally, that involve instances of women being brutalized and objects or people being contaminated. Ultimately, the thematic elements and grotesque imagery that are used in these two categories of legends are a symbolic expression of tensions surrounding the movement of women out of the home and the increased global spread of urbanism.

By now, a vast literature has attempted to answer the question of whether democracy is conducive to economic growth. The empirical side of the literature has not come to any consensus on this issue. My thesis examines Argentina's economic and political history from 1960 to the present, including particularly volatile episodes with many military regimes. Specifically, I attempt to contribute to the democracy-growth literature by examining whether Argentina's level of democracy affected its economic growth. Controlling for a number of factors, I construct an econometric model that focuses on GDP as the dependent variable and democracy as the independent variable of interest. I claim that there is no correlation between Argentina's economic growth and its level of democracy.