Estrogen

Model
Digital Document
Publisher
Florida Atlantic University
Description
Forty-eight adult Long-Evans male rats were tested
following castration for male and female sex behavior.
Following baseline test Ss received 200 mug injections of estradiol daily except on days of female tests when
20 mug of progesterone were given. Tests for male and female
behavior were alternated every third day. Significant
increases in mean lordosis and male behavior occurred
following hormone treatment. After hormone tests eight Ss received anterior lesions and five Ss received preoptic lesions. Afer recovery Ss were placed on the same schedule of hormones and tests as for the previous condition. No
significant changes in mean lordosis or male behavior occurred
following either lesion. It was concluded that estrogen is
effective in restoring male behavior and producing female
sex behavior in castrated males. While no significant changes
occurred following the lesions, it was determined that repetition and extension of the work is justified.