Note
Includes bibliography.
Member of
Publisher
Florida Atlantic University
Date Issued
2023
EDTF Date Created
2023
Description
Dose uniformity in the Planning Target Volume (PTV) can induce a higher-than-expected dose distribution in the nearby critical organs. The goal of this study is to evaluate the influence of the Planning Target volume dose uniformity on the surrounding critical organs (OAR).
Ten cases of anonymized patients’ data were selected for our study including: Breast cancer, Brain cancer, Head and Neck cancer, Lung and Prostate calculations of Conformity indices, Biological Effective Doses (BED), Tumor Control Probability (TCP) and Normal Tissue Complication Probability (NTCP) were used to calculate the dose distribution in PTV as well as the dose delivered to the surrounding critical organs of each PTV. We assume that the tumors PTVs have homogeneous density as well as the surrounding normal tissue.
Conformity indices (CI) for Breast (PTV) are between 1.8 – 1.9, for Brain (PTV) are between 1.6 – 2.0, for Lungs are 1.5 – 1.6, for Prostate are between 0.4 – 0.5, for Head and Neck are 0.3 – 0.4. Dose uniformity in all the PTVs is 1.089 which is a good indication of the quality of treatment delivered to the tumor. TCP is averaging of value of 87.94 and NTCP is 3.4445.
Ten cases of anonymized patients’ data were selected for our study including: Breast cancer, Brain cancer, Head and Neck cancer, Lung and Prostate calculations of Conformity indices, Biological Effective Doses (BED), Tumor Control Probability (TCP) and Normal Tissue Complication Probability (NTCP) were used to calculate the dose distribution in PTV as well as the dose delivered to the surrounding critical organs of each PTV. We assume that the tumors PTVs have homogeneous density as well as the surrounding normal tissue.
Conformity indices (CI) for Breast (PTV) are between 1.8 – 1.9, for Brain (PTV) are between 1.6 – 2.0, for Lungs are 1.5 – 1.6, for Prostate are between 0.4 – 0.5, for Head and Neck are 0.3 – 0.4. Dose uniformity in all the PTVs is 1.089 which is a good indication of the quality of treatment delivered to the tumor. TCP is averaging of value of 87.94 and NTCP is 3.4445.
Language
Type
Form
Extent
59 p.
Subject (Topical)
Identifier
FA00014339
Rights
Copyright © is held by the author with permission granted to Florida Atlantic University to digitize, archive and distribute this item for non-profit research and educational purposes. Any reuse of this item in excess of fair use or other copyright exemptions requires permission of the copyright holder.
Additional Information
Includes bibliography.
Thesis (PSM)--Florida Atlantic University, 2023.
FAU Electronic Theses and Dissertations Collection
Date Backup
2023
Date Created Backup
2023
Date Text
2023
Date Created (EDTF)
2023
Date Issued (EDTF)
2023
Extension
FAU
IID
FA00014339
Organizations
Attributed name: Florida Atlantic University
Attributed name: Department of Physics
Attributed name: Charles E. Schmidt College of Science
Person Preferred Name
Yigit, Erdem
author
Graduate College
Physical Description
application/pdf
59 p.
Title Plain
Dosimetric Influence of Dose due to the PTV Dose Uniformity on the Critical Organs
Use and Reproduction
Copyright © is held by the author with permission granted to Florida Atlantic University to digitize, archive and distribute this item for non-profit research and educational purposes. Any reuse of this item in excess of fair use or other copyright exemptions requires permission of the copyright holder.
Origin Information
2023
2023
Florida Atlantic University
Boca Raton, Fla.
Place
Boca Raton, Fla.
Title
Dosimetric Influence of Dose due to the PTV Dose Uniformity on the Critical Organs
Other Title Info
Dosimetric Influence of Dose due to the PTV Dose Uniformity on the Critical Organs