Note
Includes bibliography.
Member of
Contributors
Publisher
Florida Atlantic University
Date Issued
2017
EDTF Date Created
2017
Description
Sox proteins all contain a single ~70 amino acid High Mobility Group (HMG)
DNA-binding domain with strong homology to that of Sry, the mammalian testisdetermining
factor. In Drosophila melanogaster, there are four closely related members
of the B group, Dichaete (D), Sox Neuro (Sox N), Sox 21a, and Sox 21b that each exhibit
~90% sequence identity within the HMG domain.The previous study has shown that
Dichaete plays a major role in embryonic nervous system development and is expressed
in several clusters of neurons in the brain, including intermingled olfactory LNs and
central-complex neurons strongly expressed in local interneuron of the olfactory system.
However, little is known about the possible expression and functions of the related group
B Sox genes in the larval and adult brain. In particular, it is unclear if Sox N may
function along with Dichaete in controlling the development or physiology of the adult
olfactory system. Our data suggests Sox N potential role in the elaboration of the
olfactory circuit formation.
DNA-binding domain with strong homology to that of Sry, the mammalian testisdetermining
factor. In Drosophila melanogaster, there are four closely related members
of the B group, Dichaete (D), Sox Neuro (Sox N), Sox 21a, and Sox 21b that each exhibit
~90% sequence identity within the HMG domain.The previous study has shown that
Dichaete plays a major role in embryonic nervous system development and is expressed
in several clusters of neurons in the brain, including intermingled olfactory LNs and
central-complex neurons strongly expressed in local interneuron of the olfactory system.
However, little is known about the possible expression and functions of the related group
B Sox genes in the larval and adult brain. In particular, it is unclear if Sox N may
function along with Dichaete in controlling the development or physiology of the adult
olfactory system. Our data suggests Sox N potential role in the elaboration of the
olfactory circuit formation.
Language
Type
Form
Extent
129 p.
Subject (Topical)
Identifier
FA00004907
Additional Information
Includes bibliography.
Dissertation (Ph.D.)--Florida Atlantic University, 2017.
FAU Electronic Theses and Dissertations Collection
Date Backup
2017
Date Created Backup
2017
Date Text
2017
Date Created (EDTF)
2017
Date Issued (EDTF)
2017
Extension
FAU
IID
FA00004907
Organizations
Attributed name: Florida Atlantic University
Attributed name: Charles E. Schmidt College of Science
Attributed name: Department of Biological Sciences
Person Preferred Name
Singh, Shweta
author
Graduate College
Physical Description
application/pdf
129 p.
Title Plain
Characterization of Group B Sox genes in the development of Drosophila nervous system.
Use and Reproduction
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Origin Information
2017
2017
Florida Atlantic University
Boca Raton, Fla.
Physical Location
Florida Atlantic University Libraries
Place
Boca Raton, Fla.
Sub Location
Digital Library
Title
Characterization of Group B Sox genes in the development of Drosophila nervous system.
Other Title Info
Characterization of Group B Sox genes in the development of Drosophila nervous system.