Model
Digital Document
Publisher
Florida Atlantic University
Description
This microprocessor based drug infusion control system is intended to aid doctors and nurses in the care of critically ill cardiac patients. The patient's arterial blood pressure is monitored and the infusion rate of the vasodilator sodium nitroprusside is regulated based on a model reference adaptive control algorithm. The algorithm employs a reference model to approximate the patient drug response. The reference model output is compared with the patient blood pressure change and the adaptive controller parameters are changed bringing the patient drug response in closer agreement with the reference model. Drug infusion is digitally controlled by a microprocessor based system and employs a stepper motor driven peristaltic pump. Simulation studies have validated the system. Animal experiments and clinical studies will be conducted later.
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