Model
Digital Document
Publisher
Florida Atlantic University
Description
Fourteen 75-day-old female rats of the Long-Evans strain
were ovariectomized and divided into two groups of seven.
Group I received daily injections of 2mg testosterone propionate
(TP) and was tested for male sexual behavior. Group
II, in addition to daily injections of TP, also received injections
of 1mg progesterone on five of the ten test days.
This group was tested for female sexual behavior. TP was
found to exert a facilitory effect on both male and female
sexual behavior. Female sexual behavior was enhanced
further when progesterone was administered 4 to 6 hours
prior to testing. Progesterone, when injected alone, was
found to induce lordosis. It was concluded that TP was
first being converted to estrogen and it was the estrogen
which was responsible for the increase in female sexual
behavior. The fact that progesterone, which enhances
estrogen-induced lordosis, also enhances testosterone-induced
lordosis supports this position.
were ovariectomized and divided into two groups of seven.
Group I received daily injections of 2mg testosterone propionate
(TP) and was tested for male sexual behavior. Group
II, in addition to daily injections of TP, also received injections
of 1mg progesterone on five of the ten test days.
This group was tested for female sexual behavior. TP was
found to exert a facilitory effect on both male and female
sexual behavior. Female sexual behavior was enhanced
further when progesterone was administered 4 to 6 hours
prior to testing. Progesterone, when injected alone, was
found to induce lordosis. It was concluded that TP was
first being converted to estrogen and it was the estrogen
which was responsible for the increase in female sexual
behavior. The fact that progesterone, which enhances
estrogen-induced lordosis, also enhances testosterone-induced
lordosis supports this position.
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