James Kumi-Diaka

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Person Preferred Name
James Kumi-Diaka
Model
Digital Document
Description
Dementia is an umbrella term used to describe a loss of cognitive function which results in the interference
of an individual's daily life and activities. The most common form of dementia is Alzheimer's disease.
Alzheimer’s is classified as a progressive, debilitating neurodegenerative disease that results in disturbances
to a patient’s higher executive function, memory, language, and visuospatial orientation. Despite extensive
research on Alzheimer’s dementia, including both available and potential therapeutic modalities, this
neurodegenerative disease is incurable and will continue to pose a major public health concern. Current
treatment options for Alzheimer’s focus on symptom management and/or delaying the progression of the
disease. Therefore, new treatment strategies must be developed to combat such a deadly disease. One field
of medicine that has garnered significant interest from researchers to potentially treat Alzheimer’s is lowdose
ionizing radiation. Various reports suggest that the brain’s exposure to low doses of ionizing radiation
may serve as a therapeutic modality for combating neurodegenerative diseases, including Alzheimer’s
dementia. This article serves as a review of the current available treatments for Alzheimer’s disease and
discusses recent studies that provide evidence for the potential use of low-dose ionizing radiation as a
therapeutic in the treatment of Alzheimer’s disease.
Model
Digital Document
Publisher
Food Science Publisher
Description
Lifestyle significantly impacts the risk factors associated with prostate cancer, out of which diet appears to be the most influential. An emerging chemopreventive approach, which involves the adequate intake of dietary constituents, has shown great potential in preventing the occurrence or progression of cancer. Magnesium is known to be an essential cofactor for more than 300 enzymatic processes, and is responsible for the regulation of various cellular reactions in the body. A plethora of studies have shown evidence that changes in the intracellular levels of magnesium could contribute to cell proliferation and apoptosis in some normal and malignant cells. The aim of the study was to investigate the effects of magnesium chloride (MgCl2) in DU-145 prostate cancer cells.