Model
Digital Document
Publisher
Florida Atlantic University Digital Library
Description
Flosal (Jasmonal, Jasmine Aldehyde, (E)-2-benzylideneheptanal) is an important commercial fragrance compound. The principal method for its preparation involves a crossed aldol condensation reaction of heptanal and benzaldehyde. The method has a serious drawback as the synthesis of jasmine aldehyde is accompanied by self-condensation of heptanal to produce foul-smelling 2-pentyl-2-nonenal. We optimized the reaction conditions to maximize yield of jasmine aldehyde while preventing formation of 2-pentyl-2-nonenal. The desired product was obtained in ~60% yield, with a room for future improvement.
Member of